Cholesterol Drops in the West and Rises in the East

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Cardiovascular risk from the accumulation of “bad” cholesterol in blood vessels is shifting from high-income Western countries, especially those in Europe, to low- and middle-income countries, particularly in East and Southeast Asia. A meta-analysis of 1,127 studies comprising 102.6 million people worldwide shows a significant drop in bad cholesterol from 1980 to 2018 in countries such as Finland, Belgium and the U.S. and a strong rise in Thailand, Malaysia, Nigeria and Malawi. Two major factors in high-income populations are less consumption of saturated fats and widespread use of lipid-lowering medications, notably statins, says study co-leader Majid Ezzati of Imperial College London. In lower-income populations, eating saturated fats is rising, and statins are not common. Researchers had limited evidence about an emerging shift a decade ago, but Ezzati is surprised to see “just how far it has gone.”

Cholesterol Drops in the West and Rises in the East

This article was originally published with the title “Cholesterol Trades Places” in Scientific American 324, 1, 80 (January 2021)

doi:10.1038/scientificamerican0121-80

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